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Zika virus (ATCC® VR-84)

Classification: Flaviviridae, Flavivirus  /  Product Format: frozen

Classification Flaviviridae, Flavivirus
Agent Zika virus
Strain MR 766 (Original)
Biosafety Level 2

Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.

Product Format frozen
Storage Conditions -70°C or colder
Comments

The depositor reports that ATCC® VR-84™ can agglutinate goose and chicken RBC, and that this strain is non-pathogenic for hamster, guinea pig, or rabbit. 

Accidental infection has occurred in laboratory personnel

Effect on Host
Paralysis and death
Recommended Host
Suckling mouse
Growth Conditions Recommendations for Infection: Inoculate intracerebrally into suckling mice.  Resuspend 20% sMb with 7.5% BSA in PBS.
Incubation: 5-7 days
Effect on Host
Paralysis and death
Name of Depositor J. Casals, Rockefeller Foundation
Source Blood from experimental forest sentinel rhesus monkey, Uganda, 1947
Year of Origin 1947
References

Dick GW, Kitchen SF, and Haddow AJ. Zika Virus. I. Isolations and Serological Specificity. Trans R Soc Trop Med Hyg 46: 509-520, 1952. PubMed: 12995440

Zhu Z, et al. Comparative genomic analysis of pre-epidemic and epidemic Zika virus strains for virological factors potentially associated with the rapidly expanding epidemic. Emerg Microbes Infect 5: e22, 2016.