Streptomyces tacrolimicus (ATCC® 55098)

Strain Designations: MA 6858 [CIBE 9021-401]  /  Type Strain: no  /  Biosafety Level: 1

Deposited As Streptomyces sp.
Strain Designations MA 6858 [CIBE 9021-401]
Application
Produces tacrolimus FK-506, FK506
Production of the immunosuppressant FK-506
Isolation
White-tailed deer dung, Montgomery Co., VA
Biosafety Level 1

Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.

Product Format freeze-dried
Disclosure This material is cited in a US or other Patent and may not be used to infringe the claims. Depending on the wishes of the Depositor, ATCC may be required to inform the Patent Depositor of the party to which the material was furnished. This material may not have been produced or characterized by ATCC.
Preceptrol® no
Type Strain no
Medium ATCC® Medium 196: Yeast malt extract agar
Growth Conditions
Temperature: 26.0°C
Name of Depositor Merck & Co., Inc.
U.S. Patent Number
Disclosure This material is cited in a US or other Patent and may not be used to infringe the claims. Depending on the wishes of the Depositor, ATCC may be required to inform the Patent Depositor of the party to which the material was furnished. This material may not have been produced or characterized by ATCC.
Isolation
White-tailed deer dung, Montgomery Co., VA
References

Dumont F, et al. Process for producing FK-506. US Patent 5,116,756 dated May 26 1992

Martinez-Castro M, et al. Streptomyces tacrolimicus sp. nov. a Low Producer of the Immunosuppressant FK506. Int. J. Syst. Evol. Microbiol. 2010 June 4. PubMed 20525816.