Embryonic Stem Cell Products

 

ATCC Embryonic Stem Cells, Media and Reagents to Support Growth 

 

Traditional attention to quality, research and science makes ATCC your most reliable source for stem cell lines and reagents.  You can browse the stem cell lines, media and reagents below and click on the link to view the full product description and then request materials online. Click here to download a portfolio of available ES cells. These materials are also incorporated into ATCC's online catalog.

Mouse ES Cells

Our collection includes many of the most influential and widely cited mouse ES cell lines (D3, AB lines, J1, R1, R1/E, E14 derivatives). The cells are tested for markers associated with pluripotency (Oct 3/4) and to assure that the cells remained undifferentiated (alkaline phosphatase activity and SSEA-1 expression) during expansion.

ATCC® Number   Product Name Description
CRL-1934 ES-D3(D3) Derived from strain 129S2/SvPas mouse blastocyst
SCRC-1002 ES-C57BL/6 Derived from strain C57BL/6J (B6) mouse blastocyst
SCRC-1010 J1 Derived from a male agouti 129S4/Svjae embryo; useful in studies on embryonic development and Cre-Lox recombination
SCRC-1011 R1 Established from a 3.5 day blastocysts produced by crossing two 129 mouse substrains (129S1/SvlmJ and 129X1/Svj)
SCRC-1016 ESF 158 Developed from (NOD×129) F1 × 129 backcross 1 mice, intercrossed to select for homozygous regions containing disease loci; useful for genetic targeting of the nonobese diabetic (NOD) mouse genome
SCRC-1018 RW.4 Derived from a strain 129X1/SvJ mouse blastocyst; useful for gene knock-out/knock-in and studies related to differentiation and ESC proliferation
SCRC-1019 B6/BLU Derived from a C57BL/6 transgenic line containing a LacZ reporter; the transgene is a beta-globin LacZ fusion
SCRC-1020 SCC#10 Derived from a strain 129Sv/J (129X1Sv/J) mouse blastocyst; useful for gene knock-out/knock-in
SCRC-1021 EDJ#22 Derived from 129SvEV mice from Taconic; useful in gene targeting experiments
SCRC-1023 AB2.2 Originated from a Steel substrain of 129 mice (129/SvEvBrd-Hprtb-m2); useful in recombineering with a unique, fully end-sequenced, 129Sv BAC library generated from AB2.2 ES cell DNA
SCRC-1033 7AC5/EYFP A yellow fluorescent variant of R1 ES cells (129S1/SvImJ and 129X1/SvJ) generated by the random integration of EYFP using co-electroporation with a circular selectable marker containing vector pPGK Puro
SCRC-1036 R1/E Subcloned from R1 ES cells (129S1/SvImJ and 129X1/SvJ)
SCRC-1037 G-Olig2 Strain 129X1/SvJ ES line designed by the insertion of green fluorescent protein (GFP) into the gene for Olig2; the insertion permits visualization and physical separation of a subset of living ES-cell-derived neural cells
SCRC-1038 CE-1 Derived from the D3 ES line; CE1 (for Cassette Exchange) contains one ‘acceptor’ module that allows for efficient double lox targeting (the cells are hygromycin resistant)
SCRC-1039 CE3 Derived from D3 ES line; CE3 (for Cassette Exchange) contains one ‘acceptor’ module that allows for efficient double lox targeting with constitutive GFP expression (the cells are puromycin resistant)

 

Human ES Cells
 
ATCC® Number   Product Name Description
SCRC-2002 hESC BG01V BG01V cells are pluripotent and can differentiate to representatives of the three primay germ layers

 

Support Cells and Reagents for Feeder-Dependent Culture
Our classic MEF feeder cell lines, including our new antibiotic-resistant lines, are tested and validated on multiple stem cell lines for safe and robust stem cell culture. In response to customer requests, we now offer Mitomycin C, an antineoplastic antibiotic, along with the ATCC recommended protocol to prepare inactivated feeder cells.

ATCC® Number Product Name Description
SCRR-3020 Mitomycin C Antineoplastic antibiotic to prepare inactivated feeder cells
56-X IRR-STO  Irradiated STO cells
CRL-2581 C166 Mouse embryonic endothelial cell
CRL-2582 C166-GFP Mouse embryonic endothelial cell with GFP expression
CRL-2749 OP9 Mouse embryonic bone marrow stromal cells
SCRC-1007 AFT024 Mouse embryonic liver fibroblast
SCRC-1007.1 AFT024 IRR Irradiated mouse embryonic liver fibroblast
SCRC-1008 MEF (C57BL/6)[MEF-BL/6-1] Mouse embryonic fibroblast
SCRC-1008.1 MEF (C57BL/6) IRR Irradiated mouse embryonic fibroblast
SCRC-1008.2 MEF (C57BL/6) MITC Mitomycin C treated mouse embryonic fibroblast
SCRC-1040.2a MEF (CF-1) MITC Mitomycin C treated mouse embryonic fibroblast
SCRC-1040 MEF (CF-1) Mouse embryonic fibroblast
SCRC-1040.1 MEF (CF-1)IRR Irradiated mouse embryonic fibroblast
SCRC-1045 MEF (DR4) Multi-drug resistant mouse fibroblast
SCRC-1041 HFF-1 Human foreskin fibroblast
SCRC-1041.1 HFF-1 IRR Irradiated human foreskin fibroblast
SCRC-1041.2 HFF-1 MITC Mitomycin C treated human foreskin fibroblast
SCRC-1049 SNL76/7 Mouse STO fibroblast with G418 resistance and endogenous expression of LIF 
SCRC-1050 SNL76/7-4 Mouse STO fibroblast with resistance to G418 and puromycin plus endogenous expression of LIF

 

Classic Media, Supplements and Reagents to Support
Feeder-Dependent Culture

Standardized for reproducible results, our ES-cell qualified media and FBS support the most frequently used culture conditions.

ATCC® Number Description
SCRR-2010 ES-DMEM (Dulbecco's Modified Eagle's Medium, optimized for murine ES cells)
SCRR-2011 Mouse ES Cell Basal Medium
SCRR-2201 Phosphate Buffered Saline Without Calcium or Magnesium
SCRR-30-2020 Fetal Bovine Serum, ES Cell Qualified
30-2006 DMEM:F12 Medium
30-2115 L-Alanyl-L-Glutamine, 200 mM Solution in 0.85% NaCl
30-2116 MEM Nonessential Amino Acid Solution, 100x
30-2101 Trpsin EDTA Solution

 

If you have questions about the ATCC stem cell products, contact us.